"People seem to think there's an immediate reaction. It's like a sunburn: it takes a while before it shows up."
Pike was once very physically active, but when he was diagnosed with phototoxicity, allergy to the sun, he was forced to stay indoors during the bright hours of the day. As a result he started to obsess over the people outside who could move around freely, even buying a telescope so he could watch them. He became angered that they were wasting their lives and started killing them.
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Pike strangled his victims to death with a garrot wire concealed in his wristwatch. He used the cover of an eclipse or night because of his condition.
Mario Montero (attempted; the attack was interrupted)