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Louie Messer is the brother of CSI: NY's Danny Messer. He has been involved with a local gang called the Tanglewood Boys in the past. Louie was played by Larry Romano who is, coincidentally, the cousin of Carmine Giovinazzo, who plays Danny Messer.
- Danny Messer (Brother)
- Lindsay Messer (Sister-in-law)
- Lucy Messer (Niece via Lindsay and Danny)
- Nephew (Currently expecting via Lindsay and Danny)