Before joining the FBI, Avery was a mother and a psychiatrist. However her daughter's death, followed by the hacking of her private practice motivated Avery to change careers. She became the agent in charge of a department of the FBI called the Cyber Crime Division.
She teams up with the CSIs as they investigate the murder of a prominent casino owner's wife.
In the season finale, it came out that Avery has an ex-husband named Andrew Michaels as well as a daughter named Hannah. Hannah's death tore apart Avery's marriage to Andrew.
Her appearance in CSI was used to promote the newest upcoming CSI show, CSI: Cyber.
Avery is the only CSI: Cyber characters who has two Japanese dub voice actors. Her voice actor is Rica Matsumoto and Megumi Hayashibara. Interestingly, Matsumoto was voice acting Avery portrayer, Patricia Arquette in all movies and TV shows.